Portfolio
ABOUT:
Khondrion is a clinical stage biopharmaceutical company developing therapies for patients with primary mitochondrial disease (PMD). The company’s lead asset, sonlicromanol, is a potentially first-in-class, brain-penetrant redox-modulator with anti-inflammatory properties, that targets key metabolic and inflammatory pathways underlying PMD.
Learn more at khondrion.com.
ABOUT:
Napigen is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes and animals. The company is developing new gene editing technologies to provide potential cures for mitochondrial diseases.
Learn more at napigen.com.
ABOUT:
Pierrepont Therapeutics, Inc. is dedicated to developing targeted treatments for primary mitochondrial and other rare genetic diseases. Pierrepont’s lead product candidate, PTI-501 (formerly ENTR-501) is a proprietary intracellular enzyme replacement therapy for the treatment of MNGIE that is exclusively licensed from Entrada Therapeutics, Inc. (Nasdaq: TRDA).
Learn more at www.PierrepontTx.com.
ABOUT:
Pretzel Therapeutics is a Massachusetts-based company with research facilities in Mölndal , Sweden, focused on harnessing cellular energetics to modulate disease processes and improve survival, function and quality of life for a breadth of conditions. PX578, the lead development program in Pretzel’s bioenergetics portfolio, recently entered Phase 1 clinical development in the U.S.
Learn more at www.pretzeltx.com
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